The glucose test strip is expensive (especially from the long run), and each type is only applicable to the instrument they make. This is a reason why many people don't have enough tests because they cannot afford it. The goal of the project is to produce a precise blood glucose measurement system that does not require a proprietary test strip from a single manufacturer, but can (ideally) any test strip for any instrument.
A general blood glucose meter allows people to use any manufacturer's test strips to use any instruments, which can be used for any available test strips. This will allow people to purchase the best price test strips without purchasing a new instrument.
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The goal of the project is to develop a general blood glucose meter, which is:
Fully open hardware and software design (all design files, source code, etc. are open);
This can be constructed by easy access (and cheap) components. (Minimum parts);
It does not rely on a single brand test article (ideal is any brand test strip, but first placed on the test strip for measuring glucose concentrations using current measurement method, because they occupy most markets);
Ability to choose a specific brand and test bar type;
It is possible to calibrate the test strips of different production batches to ensure accuracy and calibration;
Can update the firmware to add more test strip profiles or other functions;
It is scalable, as a platform for other people to establish and add functions;
Blood glucose monitoring is permissive as possible;
Encourage others to develop other open source / open hardware blood glucose measuring methods, so that diabetic patients do not have to purchase and use dedicated disposable test strips.
The goal of this project is to become a footstone that develops a cheap, open source, reliably tracking blood sugar, which ultimately improves the life of millions of diabetic patients around the world.
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Background of the project:
I hope to find a method of measuring blood sugar, do not need a disposable special test strip. Of course, the first idea is to use some measurement methods such as blood absorption / transmittance (such as blood oxygen saturation), but it is found that this is full of problems due to interference with other compounds present in the blood. Then, the second idea is to manufacture a reusable sensor using a technique of continuous blood glucose monitors (CGM). However, after a study found that the CGM relies on the same glucose oxidase reaction, this reaction is used on the test strip and cannot be reused.
Next, focus on how the current test strip is manufactured, and it is desirable to be a lower cost manufacturing method. Currently, the production test strip does not seem to be a simple or economical choice. Next, continue to find another method, you can use the cleaning (cleaning) and reusable sensors (nothing can be discarded). It is again proven that this is difficult to achieve outside of the laboratory. Other technology: carbon nanotubes, quantum cascade lasers, dielectrometics ...
At present, the best strategy seems to build a meter that can utilize the test strips of multiple brands, and can be calibrated using a standardized glucose solution.
Test bars are the most expendituted expenditure of blood glucose levels. Therefore, it is possible to purchase a low-cost or discount (in-sale) slat without actually purchasing a new meter - expected to provide considerable savings for patients. Although you can buy inexpensive or even free meters (now you need a prescribed prescription for a specific instrument to be free), no one wants to track a meter of 4 meters, 5 meters or more, just to use the advantages of sales or discounts.
So far, it has been able to study a considerable study of current tables and decompose two meters in the project photo.
Fortunately, the functional design of the glucose meter is quite simple (and widely published). In addition, many electronic components suppliers / manufacturers and educational institutions (universities) have actually have guidelines throughout the design process.
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Some of the application description of some electronic parts manufacturers:
Titanium microcontroller in blood glucose meter
Maxim integration - tutorial 4659 blood glucose meter
Freescale Semiconductor - The Basic Principles and Design of Glucosemeters
Microchip AN1560 Blood Glucose Meter Reference Design
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In order to make the instrument can take advantage of different test bars, we need to be able to:
Adjust contact position
Adjusting bias
Use different measurement configurations:
Self-deflecting mutual resistance amplifier
Counter configures mutual resistance amplifier
Fortunately, all blood glucose test strips must respond to blood sugar concentration in linear mode (this is specified in FDA). With commercial test strips, they only need to determine their reaction to different blood sugar concentrations and use this data for linear regression (using MS XL, OpenOffice Calc, or other programs). Linear regression results provide the information required to determine the slope and intercepts required for linear equations (Y = mx + b), which is precisely required to calculate the concentration of glucose concentrations.
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Source: HackADAY.IO
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